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Table 4 Fever clearance time (FCT)

From: Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study

Statistical summary Age group 1 (6 months to <2 years) Age group 2 (2 to <6 years) Age group 3 (6 to ≤12 years)
 Censored 3 (13.6 %) 6 (12.2 %) 3 (4.3 %)
Summary (excluding censored values)
 n 19 43 67
 Mean ± SD 12.9 ± 9.37 9.1 ± 8.63 9.1 ± 7.86
 Min, max 0, 36 0, 25 0, 30
Time to fever clearance (h)  
 Quartile estimate (95 % confidence interval)  
  25 % 6.0 (6.0, 12.0) 0.0 (0.0, 6.0) 4.0 (0.0, 6.0)
  50 % (median) 12.0 (6.0, 19.0) 12.0 (6.0, 18.0) 6.0 (6.0, 12.0)
  75 % 24.0 (12.0, NE) 18.0 (18.0, 24.0) 18.0 (12.0, 18.0)
  Mean 16.0 11.0 10.0
  1. Overall, median FCT was estimated to be 10.0 h (4.0–18.0 h)
  2. NE not estimable