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Table 8 Haematological parameters (mean ± SD)

From: Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study

Parameter (unit)

Day 0

Day 2

Day 7

Day 28

Day 42

Mean haemoglobin (g/dL)

10.8 ± 1.49

9.7 ± 1.36

10.3 ± 1.39

11.4 ± 1.00

12.2 ± 1.47

Mean haematocrit

32.1 ± 4.27

28.9 ± 4.61

31.0 ± 4.19

34.5 ± 3.19

35.9 ± 3.98

Platelet count (1000/mm3)

151.5 ± 77.26

175.3 ± 65.65

325.4 ± 126.44

268.6 ± 83.53

311.9 ± 104.77

Lymphocyte (%)

29.5 ± 13.38

46.9 ± 11.88

44.8 ± 11.83

44.3 ± 11.95

45.3 ± 12.48

Eosinophils (%)

1.9 ± 2.39

3.2 ± 4.17

4.3 ± 3.96

5.8 ± 6.18

5.5 ± 5.54

Monocytes (%)

6.7 ± 5.64

8.4 ± 6.15

8.6 ± 4.55

7.5 ± 4.80

7.9 ± 5.50

White blood cells (1000/µL)

8.1 ± 3.08

7.3 ± 2.41

7.9 ± 2.92

7.2 ± 2.06

7.2 ± 2.23

Neutrophils (%)

61.7 ± 15.58

41.2 ± 14.70

42.2 ± 12.91

42.2 ± 13.84

41.2 ± 13.91