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Table 10 Protective efficacy based on mITT using a fixed effect model (meta analysis)

From: Summary of anti-malarial prophylactic efficacy of tafenoquine from three placebo-controlled studies of residents of malaria-endemic countries

Studies pooled Treatment PEa 95 % CI lower limit 95 % CI upper limit
030 and 045 Placebo    
Tafenoquine 200-mg weekly 94.1 89.7 96.6
030, 043 and 045 Placebo    
Tafenoquine 200-mg weekly 93.4 89.6 95.8
  1. CI confidence interval, mITT modified intent-to-treat
  2. aCombined estimate of PE (and CI) are based on the fixed effect model of DerSimonian and Laird [13]