Studies pooled

Treatment

Cochran’s Qtest

Between study variance^{a}

Higgins and Thompson statistics^{b}


Q Stat

P value*

H (95 % CI)

I
^{2} (95 % CI)


030 and 045

Placebo
     
Tafenoquine 200 mg weekly

0.26

0.61

0.00

1.00 (1.0, 1.7)

0.00 (0.0, 0.7)

030, 043 and 045

Placebo
     
Tafenoquine 200 mg weekly

0.70

0.71

0.00

1.00 (1.0, 1.4)

0.00 (0.0, 0.5)

 * p value is from a Chi square test of homogeneity of PE s between studies with degree of freedom k − 1, where k is the number of studies

^{a}Betweenstudy variance is estimated using the random effect model of DerSimonian and Laird [13]

^{b}
H and I
^{2} calculations are based on Higgins and Thomson [8] and 95 % confidence intervals are based on Biggerstaff and Tweedie