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Table 3 Parasitemia suppression versus untreated controls and survival in mice infected with Plasmodium berghei after oral administration of plant extracts for four days

From: In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon

Plant Part Extract Dose (mg/kg/day) % parasite ± SD (% suppression) Avg. survival ± SD (days)
Day 5 Day 7
Andropogon leucostachyus Aerial part MeOH 250 0.49 ± 0.10 (71) 1.12 ± 0.07 (48) 19 ± 2
Croton cajucara RV Leaf CHCl3 250 1.4 ± 0.27 (19) 2.2 ± 0.15 (0) 23 ± 3
Xylopia amazonica Leaf CHCl3 250 0.82 ± 0.22 (52) 1.87 ± 0.26 (11) 20 ± 2
Controls   Chloroquine diphosphate 10 0.15 ± 0.04 (91) 0.14 ± 0.04 (93) 31 ± 4
Vehicle (Blank)   1.74 ± 0.21 2.12 ± 0.31 22 ± 1
  1. CHCl 3 chloroform, MeOH methanol, SD standard deviation
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