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Table 2 Genetic diversity of parasites in (a) Asembo, Gem and Karemo areas, 2007 survey and, (b) Asembo 2001 and 2007 surveys

From: Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya

(a) Locus Asembo Gem Karemo p value
Allele no. and (richness) H e (SE) Allele no. and (richness) H e (SE) Allele no. and (richness) H e (SE) Asembo/Gem Asembo/Karemo Gem/Karemo
Polya 16 (15.94) 0.91 (0.0193) 17 (16.78) 0.89 (0.0279) 19 (18.85) 0.88 (0.0315) 0.620 0.469 0.814
Pfg377 5 (4.99) 0.47 (0.0726) 6 (5.74) 0.41 (0.0648) 5 (4.72) 0.32 (0.059) 0.472 0.073 0.316
PfPK2 10 (10) 0.85 (0.0243) 11 (10.44) 0.82 (0.0209) 12 (11.32) 0.84 (0.0221) 0.353 0.749 0.530
ADL 12 (12) 0.88 (0.0177) 14 (13.71) 0.90 (0.0114) 16 (15.28) 0.91 (0.0089) 0.205 0.075 0.550
EBP 8 (8) 0.82 (0.0562) 14 (13.4) 0.88 (0.0388) 11 (10.84) 0.83 (0.0232) 0.426 0.886 0.312
P195a 7 (6.99) 0.74 (0.0249) 6 (5.83) 0.65 (0.0206) 6 (5.99) 0.74 (0.0209) 0.005 0.957 0.003
TAA60 8 (7.98) 0.81 (0.0249) 9 (8.42) 0.79 (0.0206) 7 (6.96) 0.79 (0.0209) 0.561 0.550 0.983
TAA109 9 (8.97) 0.79 (0.0249) 12 (11.28) 0.83 (0.0169) 14 (13.17) 0.83 (0.0239) 0.124 0.178 0.993
Overall   0.78 (0.0495)   0.77 (0.0060)   0.77 (0.0661) 0.813 0.859 0.972
(b) Locus Asembo-2001 Asembo-2007 p value
Allele no. and (richness) H e (SE) Allele no. and (richness) H e (SE)
Poly-α 17 (16.92) 0.92 (0.0243) 16 (15.94) 0.91 (0.0193) 0.653
Pfg377 3 (3.00) 0.57 (0.0984) 5 (4.96) 0.47 (0.0726) 0.489
PfPK2 12 (11.92) 0.83 (0.0497) 10 (10.00) 0.85 (0.0243) 0.752
ADL 14 (13.96) 0.89 (0.0191) 12 (12.00) 0.88 (0.0177) 0.623
EBP 6 (5.99) 0.82 (0.0193) 8 (8.00) 0.82 (0.0562) 0.976
P195 11 (10.91) 0.75 (0.0241) 7 (6.99) 0.74 (0.0249) 0.733
TAA60 17 (16.87) 0.85 (0.0322) 8 (7.98) 0.81 (0.0249) 0.344
TAA109 11 (10.94) 0.77 (0.0372) 9 (8.97) 0.79 (0.0249) 0.691
Overall   0.79 (0.0380)   0.78 (0.0495) 0.625
  1. Asembo, Gem and Karemo denotes years after introduction of ITNs; 10, 9 and 3 years, respectively
  2. Comparison of genetic diversity between areas and between years was based on the number of alleles, allele richness (between areas only), unbiasied heterozygosity (H e ) and standard error (SE) [31]. Standard error was calculated to generate a p value for statistical testing of differences in H e
  3. p value <0.05 are in italics
  4. aDenotes locus with significantly different H e between areas