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Table 2 Genetic diversity of parasites in (a) Asembo, Gem and Karemo areas, 2007 survey and, (b) Asembo 2001 and 2007 surveys

From: Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya

(a) Locus

Asembo

Gem

Karemo

p value

Allele no. and (richness)

H e (SE)

Allele no. and (richness)

H e (SE)

Allele no. and (richness)

H e (SE)

Asembo/Gem

Asembo/Karemo

Gem/Karemo

Polya

16 (15.94)

0.91 (0.0193)

17 (16.78)

0.89 (0.0279)

19 (18.85)

0.88 (0.0315)

0.620

0.469

0.814

Pfg377

5 (4.99)

0.47 (0.0726)

6 (5.74)

0.41 (0.0648)

5 (4.72)

0.32 (0.059)

0.472

0.073

0.316

PfPK2

10 (10)

0.85 (0.0243)

11 (10.44)

0.82 (0.0209)

12 (11.32)

0.84 (0.0221)

0.353

0.749

0.530

ADL

12 (12)

0.88 (0.0177)

14 (13.71)

0.90 (0.0114)

16 (15.28)

0.91 (0.0089)

0.205

0.075

0.550

EBP

8 (8)

0.82 (0.0562)

14 (13.4)

0.88 (0.0388)

11 (10.84)

0.83 (0.0232)

0.426

0.886

0.312

P195a

7 (6.99)

0.74 (0.0249)

6 (5.83)

0.65 (0.0206)

6 (5.99)

0.74 (0.0209)

0.005

0.957

0.003

TAA60

8 (7.98)

0.81 (0.0249)

9 (8.42)

0.79 (0.0206)

7 (6.96)

0.79 (0.0209)

0.561

0.550

0.983

TAA109

9 (8.97)

0.79 (0.0249)

12 (11.28)

0.83 (0.0169)

14 (13.17)

0.83 (0.0239)

0.124

0.178

0.993

Overall

 

0.78 (0.0495)

 

0.77 (0.0060)

 

0.77 (0.0661)

0.813

0.859

0.972

(b) Locus

Asembo-2001

Asembo-2007

p value

Allele no. and (richness)

H e (SE)

Allele no. and (richness)

H e (SE)

Poly-α

17 (16.92)

0.92 (0.0243)

16 (15.94)

0.91 (0.0193)

0.653

Pfg377

3 (3.00)

0.57 (0.0984)

5 (4.96)

0.47 (0.0726)

0.489

PfPK2

12 (11.92)

0.83 (0.0497)

10 (10.00)

0.85 (0.0243)

0.752

ADL

14 (13.96)

0.89 (0.0191)

12 (12.00)

0.88 (0.0177)

0.623

EBP

6 (5.99)

0.82 (0.0193)

8 (8.00)

0.82 (0.0562)

0.976

P195

11 (10.91)

0.75 (0.0241)

7 (6.99)

0.74 (0.0249)

0.733

TAA60

17 (16.87)

0.85 (0.0322)

8 (7.98)

0.81 (0.0249)

0.344

TAA109

11 (10.94)

0.77 (0.0372)

9 (8.97)

0.79 (0.0249)

0.691

Overall

 

0.79 (0.0380)

 

0.78 (0.0495)

0.625

  1. Asembo, Gem and Karemo denotes years after introduction of ITNs; 10, 9 and 3 years, respectively
  2. Comparison of genetic diversity between areas and between years was based on the number of alleles, allele richness (between areas only), unbiasied heterozygosity (H e ) and standard error (SE) [31]. Standard error was calculated to generate a p value for statistical testing of differences in H e
  3. p value <0.05 are in italics
  4. aDenotes locus with significantly different H e between areas