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Table 4 Genetic differentiation index (FST) for P. falciparum populations (a) in Asembo, Gem and Karemo areas, 2007 survey and, (b) in Asembo between 1996 and 2007, and 2001 and 2007 surveys

From: Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya

(a) Locus Area1 Area2 FST Levels of differentiation
Poly-α Asembo Gem −0.003 Low
Karemo 0.001 Low
Gem Karemo −0.004 Low
Pfg377 Asembo Gem −0.003 Low
Karemo 0.005 Low
Gem Karemo −0.002 Low
PfPK2 Asembo Gem 0.007 Low
Karemo 0.001 Low
Gem Karemo 0.009 Low
ADL Asembo Gem 0.003 Low
Karemo 0.001 Low
Gem Karemo 0.006 Low
EBP Asembo Gem 0.018 Low
Karemo 0.003 Low
Gem Karemo 0.002 Low
P195 Asembo Gem 0.059 Moderate
Karemo 0.100 Moderate
Gem Karemo 0.133 Moderate
TAA60 Asembo Gem −0.006 Low
Karemo −0.011 Low
Gem Karemo −0.009 Low
TAA109 Asembo Gem 0.032 Low
Karemo 0.022 Low
Gem Karemo −0.002 Low
ALL Asembo   0.021 Low
Gem 0.021 Low
Karemo 0.021 Low
(b) Locus Survey year F ST Levels of differentiation
Poly-α 1996 2007 0.005 Low
2001 2007 −0.006 Low
Pfg377 1996 2007 0.022 Low
2001 2007 0.022 Low
PfPK2 1996 2007 0.009 Low
2001 2007 −0.001 Low
ADL 1996 2007 0.006 Low
2001 2007 0.009 Low
EBP 1996 2007 0.007 Low
2001 2007 0.013 Low
P195 1996 2007 0.105 Moderate
2001 2007 0.141 Moderate
TAA60 1996 2007 0.037 Low
2001 2007 0.057 Moderate
TAA109 1996 2007 0.037 Low
2001 2007 0.028 Low
Overall 1996 2007 0.026 Low
2001 2007 0.040 Low
  1. Genetic differentiation index (FST) was assessed at each MS between (a) any two areas of Asembo, Gem and Karemo and (b) in Asembo between 1996, 2001 and 2007 surveys’ parasite populations. This was based on the null hypothesis that alleles are drawn from the same distribution in any of the parasite populations tested. The levels were defined as little-to-low FST (<0.05), moderate (≥0.05 to <0.15) and great differentiation (≥0.15) as described previously [37]
  2. Moderate FST was highlighted in bold