Fig. 3

TK-expressing parasites become sensitive to BrdU toxicity. a MSF assay on WT and two different TK-expressing parasite lines, +TK and +TK(B), over a BrdU range of 1–0.46 mM. Error bars show standard deviation of triplicate readings. b MSF assay on the same parasites as in (a), over a range of 5–2.3 nM BrdU. IC50 values were calculated with GraphPad Prism software, 95 % confidence intervals are given in parentheses