Table 2 Baseline characteristics of subjects diagnosed with early HMS (e-HMS), re exposed versus not re exposed to malaria transmission before follow up
Characteristic | All (n = 81) | Re-exposed (n = 46) | Not re-exposed (n = 32) | p value |
|---|---|---|---|---|
Age, years [median (IQ range)] | 53.4 (38.9–60.9) | 54.0 (49.3–61.0) | 37.5 (25.2–60.1) | 0.003 |
Gender (F/M) | 31/50 | 19/27 | 11/21 | 0.536 |
Ethnicity (Caucasian/other) | 62/19 | 45/1 | 14/18 | 0.000 |
Exposure, years [median (IQ range)] | 20.0 (12.5–28.5) | 17.5 (9.5–29.0) | 22.0 (16.5–27.5) | 0.124 |
Presence of symptoms, Y/N | 74/6 | 40/5 | 31/1 | 0.391 |
Spleen diameter, cm [median (IQ range)] | 14.0 (13.0–15. 0) | 14.0 (12.9–15.0) | 15.0 (14.0–15.5) | 0.011 |
Presence of hepatomegaly, Y/N | 30/50 | 20/25 | 10/22 | 0.242 |
Hb, mg/dL [median (IQ range)] | 12.3 (11.0–13.3) | 12.3 (11.4–13.2) | 12.3 (10.8–14.0) | 0.870 |
RBC × 106/µL [median (IQ range)] | 4.1 (3.7–4.7) | 4.1 (3.7–4.3) | 4.6 (3.8–4.8) | 0.042 |
Plt × 103/µL [median (IQ range)] | 170.0 (137.0–217.0) | 169.0 (149.5–214.0) | 183.0 (123.0–217.5) | 0.674 |
ESR, mm/h [median (IQ range)] | 25.0 (14.0–47.0) | 25.0 (13.0–51.0) | 23.5 (14.5–41.0) | 0.905 |
IgM, g/L [median (IQ range)] | 2.9 (1.9–3.8) | 2.9 (2.1–4.7) | 2.2 (1.6–3.6) | 0.229 |
Plasmodium in blood, Y/N | 26/33 | 14/16 | 11/15 | 0.743 |