Table 4 Correlation between SNP frequencies and treatment outcomes
Treatment outcome | SNPs | pfmdr1 >copy | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
pfmdr1 86 | pfmdr1 1246 | Pfatp6 769 | pfK13 | |||||||
N86 | 86Y | 86 N + Y | D1246 | 1246Y | S769 | 769 N | wt | mutant | ||
ACPR | 74.1 % (n = 63) | 17.6 % (n = 15) | 8.2 % (n = 7) | 99 % (n = 88) | 1 % (n = 1) | 100 % (n = 93) | 0 | 100 % (n = 12) | 0 | 13 % (n = 12/92) |
Treatment failure | 66.6 % (n = 6) | 22.2 % (n = 2) | 11.1 % (n = 1) | 100 (n = 7) | 0 | 100 % (n = 10) | 0 | 100 % (n = 9) | 0 | 11 % (n = 1/9) |
Total (n) | 69 | 17 | 8 | 95 | 1 | 103 | 0 | 21 | 0 | 13 |