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Fig. 6 | Malaria Journal

Fig. 6

From: Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics

Fig. 6

Relationship between pLDH units and total parasite bio-burden in mice (n = 16) infected with Plasmodium berghei ANKA luciferase. a Bio-luminescence measured as average radiance [p/s/cmA2/sr] plotted on a logarithmic scale vs days post infection. b Mean concentration of pLDH units in whole blood obtained from infected mice days post infection. c Mean peripheral blood parasitaemia curves in infected mice as determined by microscopy. d Correlation between the pLDH units and mean parasitaemia, showing the coefficient correlation (r = 0.2445). e Correlation between the pLDH units and log average radiance, showing the coefficient correlation (r = 0.6992). Error bars represent mean ± SE of biological replicates. At day 1, the OD values for the infected mice were less than the control (naïve mouse blood)

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