Fig. 3

Endogenous levels of haemopexin are associated with susceptibility to experimental cerebral malaria. a BALB/c mice are more resistant to ECM than C57BL/6 mice as demonstrated by improved survival (pooled data from two biological replicates; n = 15–17 per group; log rank test, **p < 0.01). Both strains of mice had similar levels of b parasitaemia throughout the course of infection (representative data from a single experiment; n = 7-8/group); c BALB/c mice had higher levels of plasma mouse (m) haemopexin compared to the more susceptible C57BL/6 mice when moribund (pooled data from two biological replicates; n = 12–13/group). mHpx Mann–Whitney test; **p < 0.01