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Table 1 Mass spectrometer settings and MS parameters used for the detection of the test compounds on an API 3200 Q-Trap

From: Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model

Parameter Compound 1 Compound 2
Q1 mass (Da) 531.2 490.2
Q3 mass (Da) 91.1 261.2
Dwell time (ms) 40 40
Declustering potential (V) 91 61
Collision energy (V) 89 73
Entrance potential (V) 10 10
Collision cell exit potential (V) 4 2
Source temperature (°C) 500 500
Curtain gas (psi) 25 25
Gas 1 (psi) 50 50
Gas 2 (psi) 70 70
CAD gas Medium Medium
Ion spray voltage (kV) 5500 5500
Ionization mode Positive Positive