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Table 2 Sensitivity, specificity, positive predictive value and negative predictive value of the RT-PCR performed on simulated samples

From: An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples

Species test P. falciparum P. vivax
Positive Negative Positive Negative
Species-specific RT-PCR
 Positive 522 0 154 0
 Negative 2 451 2 876
McNemar’s (two-tailed) test P = 0.4795
Percentage 95 % CI Percentage 95 % CI
 Sensitivity 100 99.30–100 100 97.66–100
 Specificity 99.56 98.41–99.95 99.77 99.18–99.97
 PPV 99.62 98.63–99.95 98.73 95.50–99.85
 NPV 100 99.19–100 100 99.58–100