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Table 3 Bias of SCR estimates before and after a change in transmission assuming the true change point known

From: Sample size and power calculations for detecting changes in malaria transmission using antibody seroconversion rate

   

True time point for change in transmission

3 yearsb

5 yearsb

10 yearsb

SCR beforea

SCR aftera

Sample size

SCR before

SCR after

SCR before

SCR after

SCR before

SCR after

0.0969

0.0324

250

7.6

−7.7

9.3

−3.6

15.9

−1.9

  

500

2.5

−1.4

4.4

−0.4

8.1

0.1

  

1000

1.4

−5.4

1.6

0.2

4.3

0.0

  

2,500

0.4

1.0

1.4

0.0

1.1

−0.5

0.0969

0.0108

250

2.3

−6.7

5.9

1.1

11.1

−1.2

  

500

1.0

0.8

4.4

−2.7

5.6

0.1

  

1000

0.6

1.8

0.8

0.5

2.5

0.2

  

2500

0.2

−0.3

1.0

−1.4

1.5

−0.4

0.0324

0.0108

250

6.9

−6.6

12.3

−5.6

36.5

−2.9

  

500

5.3

−4.8

4.8

−3.2

13.2

−0.3

  

1000

1.5

0.0

3.0

−1.7

5.0

−0.4

  

2500

0.1

0.4

1.6

0.5

3.0

−0.1

0.0324

0.0108

250

4.1

11.0

8.5

−2.8

20.0

−1.5

  

500

2.9

12.7

4.4

−6.6

7.1

0.5

  

1000

1.4

−1.1

1.5

2.2

3.2

1.2

  

2500

0.9

−1.7

0.8

−0.7

1.0

−0.3

  1. aExpected number of events per year
  2. bYears before sampling