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Fig. 1 | Malaria Journal

Fig. 1

From: Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

Fig. 1

Recombinant proteins expressed in HEK293 cells. a Representation of IT4-VAR19 domain organization and sequence limits of the full-length IT4-VAR19 and the recombinant IT4-VAR19 domains studied (VAR19-NTS-DBLɣ6 and CIDRα1.1). IT4-VAR19 is composed of five Duffy-binding-like domains (shown in green), two cysteine-rich interdomain regions (shown in red), a transmembrane segment and an acidic C terminus sequence (ATS, shown in blue). b SDS-PAGE under reducing and non-reducing conditions of purified VAR19-NTS-DBLɣ6 and CIDRα1.1. c SDS-PAGE under reducing and non-reducing conditions of purified recombinant EPCR proteins (His tagged EPCRH and His/FLAG tagged)

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Malaria Journal

ISSN: 1475-2875

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