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Table 4 Adverse events associated with artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) treatment in Owando health facilities

From: Malaria burden and anti-malarial drug efficacy in Owando, northern Congo

Adverse events

ASAQ (n/N; %)

AL (n/N; %)a

Day 1

Day 2

Day 3

Total

Day 1

Day 2

Total

Asthenia

4/61; 5.6

6/61; 9.8

3/59; 5.1

13/181; 7.2

1/57; 1.8

1/56; 1.8

2/113; 1.8

Vomiting

3/61; 4.9

0/61; 0

0/59; 0

3/181; 1.6

1/57; 1.8

0/56; 0

1/113; 0.9

Headache

0/61; 0

1/61; 1.6

0/59; 0

1/181; 0.6

0/57; 0

0/56; 0

0/113; 0

Urticaria

0/61; 0

1/61; 1.6

0/59; 0

1/181; 0.6

0/57; 0

0/56; 0

0/113; 0

Abdominal pain

1/61; 1.6

1/61; 1.6

1/59; 1.7

3/181; 1.7

0/57; 0

0/56; 0

0/113; 0

Total

8/61; 13.1

9/61; 14.8

4/59; 6.8

21/181; 11.6†

2/57; 0.7

1/56; 0.4

3/113: 2.7†

  1. N number of patients followed up, n number of patients with adverse events
  2. aThere were no reported adverse events on day 3 in the AL group
  3. †There was a statistically significant difference (p = 0.004) in the proportions of ASAQ- and AL-treated patients reporting adverse events