Comparison of the safety and efficacy of fixed-dose combination of arterolane maleate and piperaquine phosphate with chloroquine in acute, uncomplicated Plasmodium vivax malaria: a phase III, multicentric, open-label study

Table 5 Fever clearance time (FCT) (intent to treat population)

Statistical summary	AM + PQP	Chloroquine
Time to fever clearance (hours)
Quartile estimate (95 % confidence interval)
25 %	12.0 (12.0, 18.0)	12.0 (6.0, 12.0)
50 % (median)	24.0 (18.0, 30.0)	24.0 (18.0, 30.0)
75 %	36.0 (36.0, 42.0)	42.0 (36.0, 42.0)
Mean	25.2	25.4
Log-rank test p value	0.7750

ISSN: 1475-2875