The risk of malaria in Ghanaian infants born to women managed in pregnancy with intermittent screening and treatment for malaria or intermittent preventive treatment with sulfadoxine/pyrimethamine

Table 3 Incidence rates for fevers, non-malaria fevers and anaemia (all episodes during passive surveillance)

Analysis population, Intervention group	Fever episodes	Person-years at risk	Incidence rate per year	Rate ratio^a (95 % CI)	p value*
ATP1, IPTp-SP	356	312.7	1.14	(Reference)	–
ATP1, ISTp-AL	336	308.5	1.09	0.99 (0.83, 1.17)	0.88

Analysis population, Intervention group	Non-malaria fever episodes	Person-years at risk	Incidence rate per year	Rate ratio^a (95 % CI)	p value*
ATP1, IPTp-SP	262	312.7	0.84	(Reference)	–
ATP1, ISTp-AL	251	308.5	0.81	0.97 (0.83, 1.15)	0.74

Analysis population, Intervention group	Anaemia episodes	Person-years at risk	Incidence rate per year	Rate ratio^a (95 % CI)	p value*
ATP1, IPTp-SP	59	312.7	0.19	(Reference)	–
ATP1, ISTp-AL	63	308.5	0.20	0.95 (0.83, 1.10)	0.52

IPTp-SP intermittent preventive treatment with sulfadoxine/pyrimethamine, ISTp-AL screening with a rapid diagnostic test (RDT) and treatment with artemether–lumefantrine, ATP1 primary analysis according to protocol
* Two-sided p values
^aCovariates adjusted: for gender, socio-economic status, rural/urban residence location, irrigated area residence location, season, ITN use, age at visit, mother’s parasitaemia status on day of enrolment into the initial cohort, predelivery haemoglobin

ISSN: 1475-2875