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Table 2 Phenotype and genotype outcomes of patient K1368

From: Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

Patient ID

Phenotype

D3 Parasite positive

Gametocyte D7 positivity

Mosquito infection

Recurrent parasitaemia

PCR correction

K1368

No

No

No

Day 42

New infection

Patient ID

Genotype

D0 Pfk13 at 578

D3 Pfk13 at 578

D0 Pfmdr1 at 86/184/1246

Day 0 Pfcrt at 72–76

D0 PfAP2mu S160 N

K1368

S

A

NFD

CVMNK

S

  1. The patient phenotypic data show typical normal clearing parasites and all samples before treatment show the wild type alleles with the exception of pfk13, where the mutant is present at codon 578. However, 3 days after treatment only the wild type of codon 578 was observed. When the pfk13 genotyping on day 3 was repeated no amplification was observed