Patient ID | Phenotype |
---|
D3 Parasite positive | Gametocyte D7 positivity | Mosquito infection | Recurrent parasitaemia | PCR correction |
---|
K1368 | No | No | No | Day 42 | New infection |
Patient ID | Genotype |
---|
D0 Pfk13 at 578 | D3 Pfk13 at 578 | D0 Pfmdr1 at 86/184/1246 | Day 0 Pfcrt at 72–76 | D0 PfAP2mu S160 N |
---|
K1368 | S | A | NFD | CVMNK | S |
- The patient phenotypic data show typical normal clearing parasites and all samples before treatment show the wild type alleles with the exception of pfk13, where the mutant is present at codon 578. However, 3Â days after treatment only the wild type of codon 578 was observed. When the pfk13 genotyping on day 3 was repeated no amplification was observed