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Table 2 Comparison between PfHRP-2/pLDH RDT and LM for detecting Plasmodium falciparum malaria in Mawza District, Taiz Governorate, Yemen

From: Field evaluation of a PfHRP-2/pLDH rapid diagnostic test and light microscopy for diagnosis and screening of falciparum malaria during the peak seasonal transmission in an endemic area in Yemen

   LM
RDT Positive Negative Total % Agreement (Kc) p value
Overall Positive 52 108 160 77.9 (0.390) <0.001
Negative 0 328 328   
Total 52 436 488   
Febrile Positive 45 3 48 94.0 (0.638) <0.001
Negative 0 3 3   
Total 45 6 51   
Afebrile Positive 7 105 112 76.0 (0.090) <0.001
Negative 0 325 325   
Total 7 430 437   
  1. PfHRP-2 P. falciparum histidine-rich protein-2, pLDH Plasmodium lactate dehydrogenase, RDT rapid diagnostic test, LM light microscopy0, Kc Cohen’s kappa coefficient;  % agreement was calculated by summation of the number of positives and negatives by both RDT and LM divided by the total number of cases