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Table 1 Specific research areas identified, by thematic area

From: Establishing research priorities for malaria elimination in the context of the emergency response to artemisinin resistance framework-the Cambodian approach

Thematic area Research areas
Malaria epidemiology, surveillance and response Mapping of mobile migrant populations (MMPs) (malaria burden in MMPs; Information on MMP status for every case in the MIS; prophylaxis for malaria control in MMP)
Improved case surveillance (case-based surveillance with GIS (low endemic settings); detailed malaria risk maps; Real time cross-border surveillance to be used by both the countries; follow up surveillance for directly observed therapy (DOT) adherence)
Malaria case management Asymptomatic cases and active surveillance and treatment
Feasibility of conducting DOTs for malaria cases
Use of microscopy as a primary method of laboratory confirmed diagnosis for malaria and establishment of a quality control program
Control of malaria vectors Vector Mapping—Changing environment/Epidemiology/variation across the country requires research into vectors (changing biting patters, life-cycle, species, exo/endophilic, etc.)
Insecticide resistance: research into potential pyrethroid resistance/insecticide efficacy
Bed net research—Good national coverage, but how effective are they, are they protecting the most at risk populations (mobile migrant workers); Sleeping behaviour of the net use net preference studies (hammocks, texture, colour)
Malaria behavioural issues How Does DOT change behaviour of the patients? Adherence of DOTs
Huge investments in DOTs—are they worth it?
How can we increase participatory village interventions? Active community involvement?
How can we increase the malaria education provided to patients by health facilities/village malaria workers (VMW)?
How best to communicate with MMPs/forest goers?
Malaria clinical studies New ACTs drug efficacy, Artesunate + Pyronaridine
First line treatment drug efficacy (Pf, Pv)
Safety of primaquine (G6PD Screening)
Other vector borne diseases (Dengue, NTDs and STHs) Dengue/chikungunya surveillance and estimation of disease burden—lacking in adult and private sector
To determine a sustainable, effective and ecologically safe vector control measure for dengue control
NTD surveillance and estimation of disease burden—lacking in private sector
NTD surveillance and vector control