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Table 1 Cost components and unit costs considered in the analytical model

From: Cost-effectiveness analysis of rapid diagnostic tests for G6PD deficiency in patients with Plasmodium vivax malaria in the Brazilian Amazon

Items

Cost per patient (unit costs, US$)

Sources base-case/variations

Base-case

Variations

Diagnosis of P. vivax malária

 Thick blood smeara

1.31

0.27–2.00

[40] / [35]–[40]

 Microscopea

0.75

0.60–0.90

[41] /± 20 %

 Microscope maintenancea

0.06

0.05–0.07

[41] /± 20 %

 Health workersa

3.48

2.78–4.18

[42] /± 20 %

 Annual training (microscopist)a

5.67

4.54–6.80

[35] /± 20 %

Drug treatment for P. vivax (therapeutic scheme)

 Males without G6PDdb

0.23

0.18–0.28

[43] /± 20 %

 Males with G6PDdb

0.12

0.10–0.14

[43] /± 20 %

 Males with G6PDd/prophylactic treatmentb

0.28

0.22–0.34

[43] /± 20 %

G6PDd diagnosis

 Training (RDT)c

0.80

0.64–0.96

[35] /± 20 %

CS-G6PD

 Health workerd

1.74

1.39–2.09

[42] /± 20 %

 One test

1.50

1.20–1.80

[44, 45] /± 20 %

 Suppliese

0.10

0.08–0.12

[46] / [46]–[46]

BX-G6PD

 Health workerd

2.04

1.63–2.45

[42] /± 20 %

 One test

5.88

4.70–7.06

[47] /± 20 %

 Suppliese

1.09

0.87–1.31

[45, 46] / [46]–[46]

Assistance to carriers of G6PDd treated with PQ

 Pre-admission testsa

10.69

9.65–11.38

[4, 40] / [4, 40]

 Medical appointmentsa

4.63

[48] /–

 Hospitalization (AIH)f

198.81

159.05–238.57

[49] /± 20 %

 Hospital fooda

68.72

54.98–82.46

[50] /± 20 %

  1. Brazilian Amazon, 2013
  2. aCosting previously detailed by Peixoto et al. [6]
  3. bTherapeutic schemes: chloroquine for 3 days and PQ for 7 days (males without G6PDd); chloroquine for 3 days (males with G6PDd) and prevention of relapse with chloroquine weekly for 12 weeks (prophylactic treatment)
  4. cBased on the cost of one training period per year per municipality for the diagnosis of malaria with RDT OptiMal® in the Brazilian Amazon
  5. dCost per test based on the average salary of Amazonas State in 2013
  6. eVariation obtained from the minimum and maximum cost identified in the time series of prices of bank (BPS) within the Ministry of Health (MoH) in 2013
  7. fCost obtained through the analysis of 108 files from the Hospital Information System (SIH/SUS) of the Brazilian Amazon in 2013