Skip to main content

Table 2 Epidemiological parameters considered in the analytic models. Brazilian Amazon, 2013

From: Cost-effectiveness analysis of rapid diagnostic tests for G6PD deficiency in patients with Plasmodium vivax malaria in the Brazilian Amazon

Parameter

Base-case

Variations

Sources base-case/variations

Proportion of malaria among febrile males seeking diagnosisa

0.0886

0.0881–0.0891

[4] /IC 95 %

Proportion of malaria cases due to P. vivax in male patientsa

0.835

0.833–0.837

[4] /IC 95 %

Prevalence of G6PDd in male patients

0.045

0.025–0.056

[7] /f]–[7] IC 95 %

Proportion of males with G6PDd hospitalized after treatment with PQb

0.943

0.744–1

[39] /± 20 %

Proportion of the use of BX-G6PDc

0.184

0.182–0.187

[4, 21] /IC 95 %

Sensitivity of CS-G6PDd

0.455

0.213–0.720

f/IC 95 %

Specificity of CS-G6PDd

0.987

0.967–0.995

f/IC 95 %

Sensitivity of BX-G6PDd, e

0.667

0.301–0.921

[16] /IC 95 %

Specificity of BX-G6PDd, e

1

0.989–1

[16] /IC 95 %

  1. aParameter obtained from the analysis of the databanks from the nine States of the Brazilian Amazon
  2. bParameter obtained from follow-up of patients with G6PDd in FMT-HVD
  3. cProportion corresponding to individuals diagnosed with P. vivax malaria, residents of municipalities with more than 100,000 inhabitants
  4. dThe cutoff point: 40 % of the median enzyme activity in the sample
  5. eThe base-case and the variation considering data from Brazil and Peru
  6. fBrito et al. Personal Communication, 2015