|
Sites
|
Immunological/age variables
|
Adjusted HR (95 % CI)
|
Wald p value
|
|---|
|
Burkina Faso
|
GLURP R2 IgG3 (values transformed to log base 10)
|
0.82 (0.74, 0.91)
|
p < 0.0001
|
|
MSP1-hybrid IgM (values transformed to log base 10)
|
0.85 (0.73, 0.98)
|
p = 0.02
|
|
Age group (months)
|
|
6–23
|
1
|
p < 0.0001
|
|
24–35
|
1.12 (0.91, 1.38)
|
|
36–47
|
0.82 (0.62, 1.07)
|
|
48–60
|
0.44 (0.31, 0.63)
|
|
Ghana
|
GLURP R2 IgG3 (values transformed to log base 10)
|
0.48 (0.25, 0.91)
|
p = 0.02
|
|
AS202.11 IgG (values transformed to log base 10)
|
1.29 (1.01, 1.65)
|
p = 0.04
|
|
Age group (months)
|
|
6–23
|
1
|
p < 0.01
|
|
24–35
|
0.14 (0.04, 0.48)
|
|
36–47
|
0.14 (0.04, 0.48)
|
|
48–72
|
0.19 (0.07, 0.55)
|
- Hazard ratios (HR) indicates the ratio of malaria hazard rates associated with a ten-fold increase in baseline antibody level
