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Table 1 Numbers of non-synonymous mutations in Plasmodium falciparum K13 gene corresponding to amino acids 210–726 in different sites in Myanmar

From: K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar

  Ann Homemalin Myit Kyi Nar Kyauk Me Phruso Total
Total n 64 91 32 13 6 206
Wild type 61** 59** 6 0 4 126
Non-propeller mutations
 R254L*    1    1
 R255K   2     2
 E294G*   1     1
 I352T   2     2
 R411K*   1     1
 Total 0 6 1 0 0 7
 % 0 6.6 3.2 0 0 3.4
 (95 % CI) (0.0–5.7) (3.0–13.6) (0.56–15.8) (0–22.8) (0–39.0) (1.7–6.8)
Propeller mutations
 P441L    1    1
 P443S   3     3
 F446I   13 18 1   32
 G449A 1     1 2
 S485N      1 1
 Y511H*    1    1
 A529T*   1     1
 N554L* 1      1
 P574L 1   2 12   15
 R561H   1     1
 R575K   1     1
 A675V   2     2
 A676D   4 3    7
 H719N   1     1
 Total 3 26 25 13 2 69
 % 4.7 28.6 78.1 100 33.3 33.5
 (95 % CI) (1.6–12.9) (20.3–38.6) (61.2–89.0) (77.2–100) (9.7–70.0) (27.4–40.2)
  1. * Newly identified mutations from this study
  2. ** Includes single samples with previously unreported synonymous mutations in Ann (E424E) and Homemalin (D343D)