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Table 2 Comparison of contents of ARS and MFQ in tablets by MIR-PLS and HPLC–MS/MS (n = 5)

From: Simultaneous quantification of artesunate and mefloquine in fixed-dose combination tablets by multivariate calibration with middle infrared spectroscopy and partial least squares regression

  Mean values ± dp (n = 3)a P value b
MIR-PLS HPLC–MS/MS
ARS 23.40 ± 0.50 22.84 ± 0.55 0.258
22.78 ± 0.43 22.24 ± 0.46 0.220
23.73 ± 0.27 22.77 ± 0.55 0.054
23.20 ± 1.52 21.55 ± 0.16 0.135
22.52 ± 0.11 22.63 ± 0.29 0.550
MFQ 49.15 ± 1.72 50.11 ± 0.75 0.428
53.77 ± 1.91 51.17 ± 0.89 0.100
51.67 ± 1.31 51.06 ± 0.22 0.471
54.14 ± 3.59 52.90 ± 0.28 0.584
52.16 ± 2.55 50.26 ± 0.13 0.266
  1. amg/100 mg of tablet
  2. bt test non-paired, at 95 % confidence level
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