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Table 3 Prevalence of pfhrp2− in false negative PfHRP-2 RDT test determined by PCR

From: Plasmodium falciparum histidine rich protein-2 diversity and the implications for PfHRP 2: based malaria rapid diagnostic tests in Ghana

  PfHRP-2 RDT− PfHRP-2 RDT+
pfhrp2 PCR− (Accra) 23 % (6/26) 36 % (34/94)
pfhrp2 PCR+ (Accra) 77 % (20/26) 64 % (60/94)
pfhrp2 PCR− (Cape Coast) 0 % (0/12) 14 % (1/7)
pfhrp2 PCR+ (Cape Coast) 100 % (12/12) 86 % (6/7)
  1. Samples that were confirmed as P. falciparum positive by PCR genotyping were grouped according to their PfHRP-2 RDT result, PfHRP-2 RDT positive (PfHRP-2 RDT+) or PfHRP-2 RDT negative (PfHRP-2 RDT−). pfhrp2 exon 2 PCR amplification was performed on each sample to estimate effect of the presence of absence of pfhrp2 on malaria diagnosis by PfHRP-2 RDT kits