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Table 1 Comparison of in vitro gametocytocidal activities with different methods and anti-malarial drugs

From: Transmission-blocking strategies: the roadmap from laboratory bench to the community

Drug IC50 uM (stage IV–V) Method References
Primaquine >10 ATP bioluminescence [107]
7.2 HTS confocal fluorescence [109]
Mefloquine 100 HTS confocal fluorescence [109]
4.7 ATP bioluminescence [107]
Pyronaridine 4.260 HTS confocal fluorescence [109]
3.2 ATP bioluminescence [107]
0.28 ATP bioluminescence [106]
Pentamidine 0.404 ATP bioluminescence [106]
2.85 HTS confocal fluorescence [109]
Methylene Blue 0.287 HTS confocal fluorescence [109]
0.49 ATP bioluminescence [107]
0.012 ATP bioluminescence [106]
Diihydroartemisin 0.00217 HTS confocal fluorescence [109]
3.56 ATP bioluminescence [107]
Artesunate 2.53 HTS confocal fluorescence [109]
2.3 ATP bioluminescence [106]
10.48 ATP bioluminescence [107]
Epoximicin 0.00042 ATP bioluminescence [107]
0.0014 Alamar Blue [108]
0.00066 HTS confocal fluorescence [109]