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Fig. 1 | Malaria Journal

Fig. 1

From: Application of magnetic cytosmear for the estimation of Plasmodium falciparum gametocyte density and detection of asexual stages in asymptomatic children

Fig. 1

Principle of Magnetic Deposition Microscopy (MDM). The cell suspension (a) is pumped through a channel comprising manifold platen with inlet and outlet ports (b), channel cut-out spacer (c) and a transparent deposition slide (d), as indicated by curved arrows. The flow channel assembly (bd) is pressed against the interpolar gap of a permanent magnet (e) generating magnetic force on the magnetically susceptible cells due to a highly non-uniform fringing field, as indicated by the magnetic energy density map (where H is the magnetic field strength in amperes per m, A/m, and B is the magnetic flux density, in tesla, T). The captured cells form a deposit (f) amenable to staining and microscopic analysis. The MDM cell deposit (g) shows enrichment in the magnetically susceptible cells compared to the original sample (h)—here the malaria parasite-infected erythrocyte culture (NF54 strain, 40× oil magnification). G gametocyte, MG male gametocyte, T trophozoite

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