| |
Phase 1: March–September 2010
|
Phase 2: October 2010–January 2013
|
|---|
|
Outcome variable
|
Hotspot clusters
|
Proportion of all mosquitoes or detected infections [%(n/N)]
|
Proportion of all survey locations in clusters [%(n/N)]
|
Proportion of survey locations under larviciding [%(n/N)]
|
Expected mosquitoes or prevalent infections
|
RR
|
p
|
Proportion of all mosquitoes or detected infections [%(n/N)]
|
Proportion of all survey locations in clusters [%(n/N)]
|
Proportion of survey locations under larviciding in [%(n/N)]
|
Expected mosquitoes or prevalent infections
|
RR
|
p
|
|---|
|
Mean catches per trap night of female An. gambiae
|
Primary cluster
|
13.6 (52/382)
|
3.7 (23/615)
|
34.8 (8/23)
|
12.89
|
4.58
|
<0.01
|
32.9 (23/70)
|
4.8 (67/1398)
|
67.2 (45/67)
|
6.10
|
5.22
|
<0.01
|
|
Secondary cluster 1
|
6 (23/382)
|
3.6 (22/615)
|
68.2 (15/22)
|
2.32
|
10.54
|
<0.01
| | | | | | |
|
Secondary cluster 2
|
3.9 (15/382)
|
1.5 (9/615)
|
33.3 (3/9)
|
1.27
|
12.33
|
<0.01
| | | | | | |
|
Secondary cluster 3
|
2.4 (9/382)
|
0.2 (1/615)
|
100 (1/1)
|
1.06
|
8.72
|
0.01
| | | | | | |
|
Secondary cluster 4
|
2.1 (8/382)
|
0.2 (1/615)
|
100(1/1)
|
0.85
|
9.67
|
0.02
| | | | | | |
|
Secondary cluster 5
|
1.6 (6/382)
|
0.2 (1/615)
|
0
|
0.56
|
10.82
|
0.05
| | | | | | |
|
Total
| |
29.6% (1 13/382)
|
9.3 (57/615)
|
49.1 (28/57)
| | | |
32.9 (23/70)
|
4.8 (67/1398)
|
67.2 (45/67)
| | | |
|
Human malaria infection prevalence
|
Primary cluster
|
39.4 (148/376)
|
29.8 (78/261)
|
46.2 (36/78)
|
124.31
|
1.82
|
<0.01
|
13.4 (114/852)
|
5.8 (5/86)
|
0.6 (3/5)
|
53.98
|
2.28
|
<0.01
|
|
Secondary cluster 1
|
15.7 (59/376)
|
10.0 (26/261)
|
50 (13/26)
|
18.73
|
2.40
|
<0.01
|
5.9 (50/852
|
3.5 (3/86)
|
100 (3/3)
|
21.15
|
2.45
|
<0.01
|
|
Secondary cluster 2
| | | | | | |
7.9 (67/852)
|
3.5 (3/86)
|
0
|
35.04
|
1.99
|
<0.01
|
|
Secondary cluster 3
| | | | | | |
7.3 (62/852)
|
4.7 (4/86)
|
0
|
33.33
|
1.93
|
<0.01
|
|
Secondary cluster 4
| | | | | | |
9.9 (84/852)
|
2.3 (2/86)
|
0
|
46.22
|
1.91
|
<0.01
|
|
Secondary cluster 5
| | | | | | |
3.2 (27/852)
|
1.2 (1/86)
|
0
|
10.57
|
2.60
|
<0.01
|
|
Total
| |
55.1 (207/376)
|
39.8 (104/261
|
47.1 (49/104)
| | | |
47.4 (404/852)
|
20.9 (18/86)
|
33.3 (6/18)
| | | |
- Hotspots of An. gambiae were identified using Poisson statistical model while those of infection prevalence were detected using binomial statistical model. The significance of the cluster (p value) was calculated based on MonteCarlo replications set at 9999. RR relative risk which refers to the standardized risk ratio of observed mean catches of mosquitoes or prevalent infections (indicated by ‘n’ in a thirdcolumn) over the expected mean of mosquito densities or prevalent infections
