Fig. 4

Kinetics of atypical MBC, transitional and classical MBC proportions in participants categorized by parasite density and recent asymptomatic parasitaemia. a and b: participants were separated by day 0 parasite densities of greater than or less than 23,080 parasite/µl (green boxes, a), or by having at least one recently documented case of asymptomatic parasitaemia (purple boxes, b). c Lines were based on categories of parasite density from (a), and depict proportions of B cell sub-sets over the 28-day observation period following malaria (day 0). d Lines were based on category of asymptomatic parasitaemia from (b), and depict proportions of B cell sub-sets over the 28-day observation period following malaria (day 0). c and d Lines represent mean proportion for each group, with bars denoting 95 % confidence intervals. Asterisk, double asterisk and triple asterisk indicate a significant difference between groups at that timepoint as assessed by Wilcoxon rank sum test (p < 0.05, 0.01 and 0.001, respectively, ns = no significant difference)