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Table 4 Results of changing drug and testing protocol for anti-malarial drug distribution compared to a strategy of three rounds mass test and treat with artemether-lumefantrine at 72 % coverage per round of all ages of the population with 60 days between rounds

From: Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia’s southern province: a simulation study

% Change in median parasite prevalence (IQR) compared to baseline strategy, by pre-intervention mean parasite prevalence

%

Baseline intervention strategy

MTAT with DHAP

MTAT with DHAP + ivermectin

MDA with DHAP

MDA with DHAP + ivermectin

MDA with DHAP + SLD primaquine

MDA with DHAP + ivermectin + SLD primaquine

<10

MTAT with AL, 72 % coverage, 60 day frequency between rounds, targeting all ages

0.56

(−25.5, 52.4)

4.5

(−28.0, 50.10

−7.6

(−32.2, 25.5)

−3.6

(−30.5, 33.9)

−17.1

(−35.0, 33.6)

−12.3

(−32.8, 32.2)

10–24

−7.2

(−27.0, 15.3)

−8.8

(−28.6, 16.3)

33.0

(−56.0,16.0)

33.5

(−48.1,9.5)

35.7

(−56.7,10.8)

39.0

(−53.5,10.8)

>24

−0.2

(−11.9, 11.4)

−1.1

(−13.6, 9.7)

44.1

(−53.6,21.9)

43.6

(−56.1,33.7)

36.4

(−55.4,27.2)

40.4

(−55.1,28.4)

  1. Italics indicate results that perform better than the baseline strategy