Fig. 1

Partial NH₂-terminus and partial TSR peptides endogenously expressed from Plasmodium gallinaceum and Plasmodium falciparum. a Schematic representation of circumsporozoite protein and endogenously-expressed peptides. The open bricked block represents the signal peptide; the red block represents the NH₂-terminus; the light gray block represents the conserved motif Region I; the striped block represents the tandem repeats; the blue block represents the TSR domain; the gray block represent the region II motif and the dotted block the putative GPI anchor. b Alignment of amino acid sequences of endogenously-expressed peptides from P. gallinaceum (PG) and P. falciparum (PF) CSPs. Key: red, partial NH₂-terminal; light gray, Region I; asterisks, conserved amino acids; underlined, tandem repeats; blue, partial TSR; and dark gray, Region II