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Fig. 2 | Malaria Journal

Fig. 2

From: Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys

Fig. 2

Specificity of antibody response induced by immunization with rPfMSP8 (ΔAsn/Asp) versus rPfMSP1/8 vaccines. Antigen-specific IgG titres (mean ± standard deviation) in sera collected from Aotus monkeys (6 animals/group) immunized with a rPfMSP8 (ΔAsn/Asp) or b rPfMSP1/8 vaccines formulated with Montanide ISA 720 were determined by ELISA. Sera collected 2 weeks following primary, secondary and tertiary immunization were evaluated. ELISA plates were coated with either rPfMSP1/8, rPfMSP8 (ΔAsn/Asp), rGST-PfMSP119 (FVO), or rGST-PfMSP119 (3D7) as indicated. For each animal, reactivity of pre-immunization serum was subtracted as background

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