Fig. 5From: Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiologyColony formation assays for BY4741 and BY4741/Δvma yeast expressing the indicated PfCRT isoform, PMA-chimera, or empty vector (EV). Top panels show equal growth for all strains in non-inducing media. Bottom left (BY4741, inducing media) shows intrinsic toxicity of PH1 and PH2 expression in the BY4741 parental strain. Bottom right (BY4741/Δvma1, inducing media) shows conditional lethality of PH1 and PH2 expression in BY4741 yeast lacking vma subunit1Back to article page