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Table 2 Clinical and parasitological responses

From: Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study

Study site Total Myitkyina Thabeikkyin P value
Median time of fever clearance (IQR), hours 6 (6–12) 6 (6–6) 12 (6–18) 0.008**
Median parasite clearance Half-life (IQR), hours 3.3 (2.1–4.8) 4.4 (3.4–6.7) 2.6 (2.0–3.8) <0.0001**
Parasite clearance time (Median, IQR), hours 42 (30–72) 72 (42–96) 36 (24–72) <0.0001**
Parasite clearance Half-life >4 h, n/N (%) 42/114 (37.7) 27/43 (62.8) 16/71 (22.5) P < 0.001*
Parasite clearance half-life >5 h, n/N (%) 26/114 (22.8) 17/43 (39.5) 9/71 (12.7) P < 0.01*
Day 3 parasitaemia, n/N (%) 20/114 (17.5) 13/43 (30.2) 7/71 (9.9) P < 0.01*
Gametocyte carriage time (median, IQR), hours 18 (9–57) 57 (6–81) 16.5 (12–24) 0.31
ACPR on day 42, % (95 % CI) 100 (97–100) 100 (92–100) 100 (95–100)  
  1. ACPR adequate clinical and parasitological response
  2. * Chi square statistics
  3. ** Mann–Whitney test