Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study

Table 4 Multivariable analysis examining relationship between clearance half-life or day 3 positivity and covariates kelch 13 propeller mutations, site and admission parasitaemia

	Odds ratio	95 % confidence interval	P value
Half-life cutoff 4 h
Site (Myitkyina)	4.1	1.7–10.1	0.002
Kelch 13 (>440)	5.0	1.9–12.9	0.001
Half-life cutoff 5 h
Site (Myitkyina)	3.5	1.3–9.4	0.01
Kelch 13 (>440)	2.3	0.9–6.1	0.1
Day 3 positivity
Parasitaemia on admission (>1 % parasitaemia)	4.0	1.2–11.4	0.02
Site (Myitkyina)	3.2	1.1–9.6	0.04
Kelch 13 (>440)	2.0	0.7–4.0	0.68

ISSN: 1475-2875