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Table 1 Genes encoding P. falciparum aaRSs and their localization

From: Recent advances in the biology and drug targeting of malaria parasite aminoacyl-tRNA synthetases

Protein name

Mitochondria

Apicoplast

Cytoplasm

Class I

 Arginyl-tRNA synthetase

 

PF3D7_0913900

PF3D7_1218600

 Cysteinyl-tRNA synthetase

 

PF3D7_1015200.1

PF3D7_1015200.1

 Glutamyl-tRNA synthetase

 

PF3D7_1357200

PF3D7_1349200

 Glutaminyl-tRNA synthetase

  

PF3D7_1331700

 Isoleucyl-tRNA synthetase

 

PF3D7_1225100a

PF3D7_1332900a

 Leucyl-tRNA synthetase

 

PF3D7_0828200a

PF3D7_0622800

 Methionyl-tRNA synthetase

 

PF3D7_1005000

PF3D7_1034900

 Tryptophanyl-tRNA synthetase

 

PF3D7_1251700a

PF3D7_1336900

 Tyrosyl-tRNA synthetase

 

PF3D7_1117500

PF3D7_0807900

 Valyl-tRNA synthetase

 

PF3D7_0311200a

PF3D7_1461900

Class II

 Alanyl-tRNA synthetase

 

PF3D7_1367700a

PF3D7_1367700a

 Asparaginyl-tRNA synthetase

 

PF3D7_0509600

PF3D7_0211800

 Aspartyl-tRNA synthetase

 

PF3D7_0514300

PF3D7_0102900

 Glycyl-tRNA synthetase

 

PF3D7_1420400

PF3D7_1420400

 Histidyl-tRNA synthetase

 

PF3D7_0934000

PF3D7_1445100

 Lysyl-tRNA synthetase

 

PF3D7_1416800

PF3D7_1350100

 Phenylalanyl-tRNA synthetase

PF3D7_0603700

PF3D7_1232000

PF3D7_1104000 (α)

PF3D7_0109800a (β)

 Prolyl-tRNA synthase

 

PF3D7_0925300a

PF3D7_1213800

 Seryl-tRNA synthetase

 

PF3D7_1216000

PF3D7_071770

 Threonyl-tRNA synthetase

 

PF3D7_1126000a

PF3D7_1126000a

Other enzymes

 D tyrosyl-tRNA deacylase

  

PF3D7_1108200a

 P43

  

PF3D7_1442300

 Glutamyl-tRNA amidotransferase

 

PF3D7_0416100 (A)

PF3D7_0628800 (B)

 
  1. a Indicate genes containing editing activity