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Table 2 Descriptions of different immunological responses often discussed in malaria epidemiology (after Schofield and Mueller)

From: Large contractors in Africa: conundrums with malaria chemoprophylaxis

Clinical immunity Acquired immunity that protects against clinical illness despite presence of malaria parasites in blood
Clinical tolerance Lowered responsiveness to malaria parasite toxins
Anti-toxic immunity Acquired immunity that neutralizes parasite toxins
Anti-parasite immunity Acquired immunity that kills or inhibits growth or replication of malaria parasites
  1. Use of such terminology in the scientific literature often overlaps, is sometimes used interchangeably, and can vary subtly in its various applications