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Fig. 6 | Malaria Journal

Fig. 6

From: Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes

Fig. 6

A time-course analysis of a glycosylated primaquine (9) generated through the activity of human hepatocytes; b non-enzymatic generation of primaquine-glucose conjugates observed following the incubation of primaquine and its metabolites in cell-free hepatocyte media and; c primaquine carbamoyl-glucuronide (10) differentially generated from (+)-, (−)-and (±)-primaquine in vitro in human hepatocytes. Each point represents value mean ±SD of four observations

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