Fig. 1

Patient flow diagram. After enrolment to the studies, patients admitted to Mae Sot Hospital had blood collected prior to paracetamol administration followed by timed blood collections. Group 1 received oral syrup paracetamol (PO) on day 0 then intramuscular paracetamol (IM) on day 1; Group 2 received intramuscular paracetamol on day 0 then oral syrup paracetamol on day 1. One patient in Group 1 did not receive the intramuscular dose of paracetamol on day 1 due to self-discharge from the hospital; one patient from Group 2 did not receive oral paracetamol on day 1 as the patient received multiple doses of paracetamol during the study period. All patients were included in the pharmacokinetic analysis