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Fig. 3 | Malaria Journal

Fig. 3

From: Development of a Plasmodium berghei transgenic parasite expressing the full-length Plasmodium vivax circumsporozoite VK247 protein for testing vaccine efficacy in a murine model

Fig. 3

Developmental characteristics and the infectivity and fitness of profiles of PvCSP(VK247)/Pb parasites in Anopheles stephensi mosquitoes. The number of oocysts per mosquito and the percentage of infected mosquitoes were comparable among the WT-Pb (n = 120), PvCSP(VK210)/Pb (n = 120), and PvCSP(VK247)/Pb (n = 120) groups. a Midgut oocysts in the mosquitoes were examined 14 days after an infectious feed. Data are the mean number of oocysts observed (± SEM). b Salivary gland sporozoites in mosquitoes were examined 21 days after an infectious feed. Data are the mean number of sporozoites observed (± SEM). Percentages on top of the panels indicate the infectivity rates. Statistical significance was determined by the Kruskal–Wallis test (oocyst or sporozoite intensity) or Fisher’s exact probability test (oocyst or sporozoite prevalence). *P < 0.05

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