Fig. 4
Specificity of Cys versus N-acetyl-Cysteine in potentiation of ARTM in Plasmodium chabaudi blood-stage infection. Mice (minimum of 5 mice per group) were infected by 107 P. chabaudi pRBC through the i.v. route, and blood parasitaemia was monitored (a), and mortality was recorded (b), as described in legend of Fig. 2. The results show that at equivalent concentrations, Cys (70 mg/kg) can strongly potentiate the anti-plasmodial activity of ARTM (0.2 mg/kg), while NAC (70 mg/kg) has no effect. Statistical significance was calculated by unpaired student t test, *p < 0.05. Data are from one of two independent experiments that produced similar results