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Table 2 Incidence rate and hazard ratios for Plasmodium vivax episodes according to exposure status

From: Declining malaria transmission in rural Amazon: changing epidemiology and challenges to achieve elimination

 

N episodes

Person-years of follow-up

Rate (episodes/100-PY) (95 % CI)

Univariable IRR (95 % CI)

P value

Multivariable IRR (95 % CI)

P value

Gender

Female

279

802

34.8 (31.0–39.1)

1

0.151

1

0.204

Male

377

998

37.8 (34.2–41.8)

1.2 (0.9–1.5)

1.2 (0.9–1.5)

Age (years)

0–10

194

451

43.0 (37.3–49.5)

1

 

1

 

10–20

143

436

32.8 (27.8–38.6)

0.7 (0.6–1.0)

0.059

0.7 (0.5–0.9)

0.038

20–40

163

429

38.0 (32.6–44.3)

0.9 (0.7–1.3)

0.709

1.0 (0.7–1.3)

0.954

40–60

114

328

34.7 (28.9–41.7)

0.9 (0.6–1.2)

0.461

0.9 (0.6–1.3)

0.524

≥60

42

153

27.3 (20.2–36.9)

0.7 (0.5–1.2)

0.195

0.8 (0.5–1.2)

0.229

Socio-economic status

Lowest quintile

258

702

36.7 (32.5–41.5)

1.0 (0.8–1.2)

0.798

0.9 (0.7–1.1)

0.422

2nd–4th quintiles

284

707

40.2 (35.8–45.1)

1

 

1

Highest quintile

114

320

35.6 (29.6–42.7)

1.0 (0.7–1.3)

0.825

0.9 (0.7–1.2)

Season

Rainy

238

750

31.7 (27.9–36.0)

1

0.007

1

<0.001

Dry

418

1049

39.9 (36.2–43.9)

1.2 (1.1–1.5)

1.4 (1.1–1.6)

Use of ITN

No

362

857

42.3 (38.1–46.8)

1

0.199

1

0.001

Yes

294

943

31.1 (27.8–35.0)

0.9 (0.7–1.1)

0.7 (0.6–0.8)

IRS in last 6 months

No

149

530

28.1 (23.9–33.0)

1

0.015

1

0.002

Yes

507

1200

42.3 (38.7–46.1)

1.4 (1.1–1.8)

1.4 (1.1–1.8)