Skip to main content

Table 1 Evolutionary relationship levels of malaria vaccine candidates that have reached clinical trials

From: An evolutionary approach to identify potentially protective B cell epitopes involved in naturally acquired immunity to malaria and the role of EBA-175 in protection amongst denizens of Bolifamba, Cameroon

Level 1 Level 2 Level 3 Level 4 Level 5 Level 6
0 PF3D7_0603400 (TEX1) 0 PF3D7_1216600 (CelTOS) 0 PF3D7_1200600 (VAR2CSA)
  PF3D7_1133400 (AMA1)   PF3D7_1031000 (Pfs25)   PF3D7_1035300 (GLURP)
    PF3D7_1346700 (P48/45)   PF3D7_1035400 (MSP3)
    PF3D7_1335900 (TRAP)   PF3D7_1036400 (LSA1)
    PF3D7_0930300 (MSP1)   PF3D7_0206800 (MSP2)
    PF3D7_0207600 (SERA5)   PF3D7_1121600 (EXP1)
    PF3D7_0404500 (P52)   PF3D7_0406200 (Pfs16)
    PF3D7_0404400 (P36)   PF3D7_0102200 (RESA)
    PF3D7_0304600 (CSP)   PF3D7_0702300 (STARP)
    PF3D7_0731500 (EBA175)   PF3D7_0220000 (LSA3)
  1. Levels correspond to phylogenetic relationships defined in Fig. 2. Genes are identified by their official ID number and protein name in parentheses