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Fig. 4 | Malaria Journal

Fig. 4

From: The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

Fig. 4

Representative opsonization activity and fitting. Representative data for opsonization activity at serial dilutions (1:100, 1:500, 1:2500, 1:12,500, 1:62,500) for two measures of opsonization: the frequency of cells undergoing phagocytosis (Mfreq, top) and the mean fluorescence intensity (MFI, bottom) of cells undergoing phagocytosis. Opsonization activity (circles) is shown after subtracting pre-immune serum activity. Examples of low (left), medium (middle), and high (right) opsonization titres are shown. The four-parameter curve fitted to the data is shown in red, the horizontal line indicates the opsonization activity at 60 % of maximum activity, and the vertical line indicates the log dilution corresponding to 60 % maximum activity, as determined by the fitted curve

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