Skip to main content
Fig. 6 | Malaria Journal

Fig. 6

From: Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2

Fig. 6

The hypothetical model of trafficking pathway involved in PfRab5b. N-acylated proteins, such as PfAK2, are recruited to novel compartment(s) adjacent to the ER, and packed into the multivesicular body or an autophagosome-like double membrane structure together with PfRab5b. The multivesicular body fuses with the PPM, and internal vesicles fuses with the PVM. Rab5b is clustered on the TVN. Nuc, nucleus; RBC, red blood cell; PTEX, Plasmodium translocon of exported proteins; PAT, palmitoyltransferase. EVP1 and SBP1 are exported proteins with and without the Plasmodium export element (PEXEL) signal, respectively

Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us