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Table 2 T cell data

From: Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection

Parameter Values for indicated group [median (IQR)] or individual values
Control Asymptomatic Acute uncomplicated
Sub-microscopic Sub-microscopic Patent Patent Malaria Malaria
P. falciparum P. vivax P. falciparum P. vivax P. falciparum P. vivax
No. of subjects 70 17 12 12 18 6 8
CD4 T cells/µl blood 752 (611–914) 570 (478–699)a 733 (634–1165) 836 (539–1041) 773 (588–941) 201 (117–351)** 243 (170–321)***
CD25+ CD127low CD4+ Treg cells/µl blood 42 (33–53) 36 (28–46) 44 (40–59) 41 (33–66) 41 (30–54) 14 (11–23)** 16 (11–21)***
% of Treg cells in CD4 T cells 5.4 (4.6–6.2) 6.1 (5.2–7.2) 6.0 (4.1–6.9) 6.3 (5.4–7.1) 5.3 (4.4–6.5) 6.9 (5.7–9.7) 6.3 (5.6–7.4)
CD45RA CD25high aTreg/µl blood 8.0 (6.1–11.2) 7.7 (5.9–10.2) 8.2 (6.6–12.9) 7.1 (2.8–9.9) 6.0 (5.3–7.3)a 3.9 (2.6–5.0)* 4.3 (3.3–7.4)a
% of aTreg in total Treg cells 20.7 (16.2–25.8) 23.5 (17.9–28.0) 19.8 (15.3–22.9) 11.9 (8.6–16.4)** 14.8 (13.0–18.1)a 25.2 (20.1–33.8) 29.2 (26.3–44.4)*
CD45RA+ CD25+ rTreg/µl blood 12.3 (6.6–19.3) 8.9 (6.8–13.9) 14.0 (7.6–20.0) 11.7 (9.3–19.3) 10.0 (7.2–17.8) 4.4 (3.1–6.0)* 2.9 (1.7–4.1)***
% of rTreg in total Treg cells 31.7 (20.5–36.9) 29.3 (21.1–35.2) 27.7 (21.1–35.5) 30.8 (22.3–36.2) 28.6 (23.4–38.4) 30.2 (19.1–33.4) 19.4 (14.2–20.5)*
rTreg/aTreg ratio 1.3 (0.9–1.9) 1.0 (0.8–2.0) 1.2 (0.9–2.5) 2.3 (1.4–3.7)* 1.8 (1.3–2.7)a 1.1 (0.8–1.5) 0.7 (0.4–0.9)**
  1. IQR interquartile range
  2. Significantly different to control, Kruskal–Wallis test with Dunn’s multiple comparisons
  3. * P < 0.05
  4. ** P < 0.005
  5. *** P < 0.0005
  6. aSignificantly different to control, Mann–Whitney U test (P < 0.05)