Table 2 T cell data

No. of subjects

70

17

12

12

18

6

8

CD4 T cells/µl blood

752 (611–914)

570 (478–699)^a

733 (634–1165)

836 (539–1041)

773 (588–941)

201 (117–351)**

243 (170–321)***

CD25⁺ CD127^low CD4⁺ Treg cells/µl blood

42 (33–53)

36 (28–46)

44 (40–59)

41 (33–66)

41 (30–54)

14 (11–23)**

16 (11–21)***

% of Treg cells in CD4 T cells

5.4 (4.6–6.2)

6.1 (5.2–7.2)

6.0 (4.1–6.9)

6.3 (5.4–7.1)

5.3 (4.4–6.5)

6.9 (5.7–9.7)

6.3 (5.6–7.4)

CD45RA⁻ CD25^high aTreg/µl blood

8.0 (6.1–11.2)

7.7 (5.9–10.2)

8.2 (6.6–12.9)

7.1 (2.8–9.9)

6.0 (5.3–7.3)^a

3.9 (2.6–5.0)*

4.3 (3.3–7.4)^a

% of aTreg in total Treg cells

20.7 (16.2–25.8)

23.5 (17.9–28.0)

19.8 (15.3–22.9)

11.9 (8.6–16.4)**

14.8 (13.0–18.1)^a

25.2 (20.1–33.8)

29.2 (26.3–44.4)*

CD45RA⁺ CD25⁺ rTreg/µl blood

12.3 (6.6–19.3)

8.9 (6.8–13.9)

14.0 (7.6–20.0)

11.7 (9.3–19.3)

10.0 (7.2–17.8)

4.4 (3.1–6.0)*

2.9 (1.7–4.1)***

% of rTreg in total Treg cells

31.7 (20.5–36.9)

29.3 (21.1–35.2)

27.7 (21.1–35.5)

30.8 (22.3–36.2)

28.6 (23.4–38.4)

30.2 (19.1–33.4)

19.4 (14.2–20.5)*

rTreg/aTreg ratio

1.3 (0.9–1.9)

1.0 (0.8–2.0)

1.2 (0.9–2.5)

2.3 (1.4–3.7)*

1.8 (1.3–2.7)^a

1.1 (0.8–1.5)

0.7 (0.4–0.9)**