Fig. 3From: OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimensOptiMal-PK predictions of OZ439 clinical activity. Results of OptiMal-PK simulations on OZ439. Assuming a single dose of either 1200 mg capsule (fasted, green line), oral dispersion in fed subjects with (blue) or without (red) an assumption of 20 % reduction in t1/2 or a threefold increase in IC50 (purple)Back to article page